GLP-1 medications mimic glucagon-like peptide-1, a natural gut hormone that regulates appetite and blood sugar. By activating GLP-1 receptors, these medications reduce hunger, quiet “food noise,” and slow stomach emptying so meals keep you satisfied longer. Clinicians prescribe them for adults with obesity, or overweight with a weight-related condition, when the expected benefits outweigh the risks.
The two leading options are semaglutide, a GLP-1 medication with the longest track record in its class, and tirzepatide, a dual-action medication that targets GIP alongside GLP-1 and produced the largest average weight loss in clinical trials (compounded preparations were not studied in those trials). Both are weekly injections started at a low dose and increased gradually over months under clinician supervision.
Medical supervision matters. These are prescription medications with real contraindications, side effects that need managing, and dosing that must be individually titrated — which is why every Drip Vitals plan includes a licensed clinician's evaluation before treatment and ongoing support during it. Medication works best alongside lifestyle change: protein-focused nutrition, strength training, and sleep all compound its effect.
One thing worth understanding: compounded semaglutide and tirzepatide are prepared for individual prescriptions by licensed compounding pharmacies and are not FDA-approved — the FDA does not review compounded drugs for safety, effectiveness, or quality before marketing. Your clinician can discuss which path is appropriate for you.